Jacob C. Ulirsch

As part of a statistical genetics and experimental genomics research group, my work focuses on developing and applying novel methodologies to gain biological insights into genetic association signals. Specifically, I am involved in several projects to improve genetic fine-mapping for biobank-scale GWAS studies. Ultimately, we plan to test these results using massively parallel reporter assays and use these data to create accurate models of regulatory grammar as part of the ENCODE consortium. Additional projects include uniformly processing large single cell genomics datasets to create features and developing novel methodologies to prioritize GWAS target genes. I am a member of Hilary Finucane’s lab.