Elise Robinson is an instructor in the Analytic and Translational Genetics Unit at Massachusetts General Hospital and an affiliated scientist at the Broad Institute. She is also an instructor in the Department of Medicine at Harvard Medical School.
Robinson’s research focuses on the genetic epidemiology of behavior and cognition. She is interested in using genetic data to understand the biology of neurodevelopmental variation, and to study differences within and between psychiatric disorders. She uses data and results from large genomics consortia to examine disease patterns in population samples.
Robinson’s work to date has linked the genetic risk factors for severe neuropsychiatric disorders to variation in behavior in the general population, and has evaluated continuous trait and quantitative models of disease risk. She has also studied sex differences in psychiatric disease, as well as types of genetic risk more likely to associate with both cognition and behavior.
Robinson’s research reflects her training in epidemiology and genetics. She received a Sc.D. in psychiatric epidemiology at the Harvard School of Public Health, supervised by Dr. Karestan Koenen. She completed postdoctoral training in the lab of Mark Daly at MGH and the Broad Institute, using statistical genetic approaches to study neurodevelopmental disorders.
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.
Identification of Developmental and Behavioral Markers Associated With Genetic Abnormalities in Autism Spectrum Disorder.
Am J Psychiatry. 2017;:appiajp201716101115 - PMID: 28253736
Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples.
Overweight or about right? A norm comparison explanation of perceived weight status.
Ultra-rare disruptive and damaging mutations influence educational attainment in the general population.
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
An atlas of genetic correlations across human diseases and traits.
Genetic research in autism spectrum disorders.
Curr Opin Pediatr. 2015;:ePub - PMID: 26371945
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.
Neuron. 2015;87(6):1215-1233 - PMID: 26402605
Autism spectrum disorder severity reflects the average contribution of de novo and familial influences.
Proc Natl Acad Sci U S A. 2014;:ePub - PMID: 25288738
A framework for the interpretation of de novo mutation in human disease.
Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: Results of a phase II clinical trial.
J Clin Oncol. 2009;27(15_suppl):4512 - PMID: 27962705